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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at room temperature 3 years
- 英文名：
3,4-Dimethoxybenzoic acid
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
93-07-2
- 规格：
10 mM * 1 mL/25 g/50 g/100 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥390.0 |
|---|---|---|---|
| 规格： | 25 g | 产品价格： | ￥350.0 |
| 规格： | 50 g | 产品价格： | ￥550.0 |
| 规格： | 100 g | 产品价格： | ￥890.0 |
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Veratric acid
CAS No. : 93-07-2
MCE 国际站：Veratric acid
产品活性：Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的多酚物质，可口服，具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时，Veratric acid 能够减少上调的 COX-2 表达，降低 PGE2 和 IL-6 水平。
研究领域：Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease
作用靶点：COX | Reactive Oxygen Species
In Vitro: Veratric acid (100, 200 μM) suppresses iNOS expression in LPS-stimulated RAW264.7 cells. Veratric acid (200 μM) inhibits LPS-induced activation of the PI3K/Akt pathway, HAT activation and HDAC3 expression in RAW264.7 cells.
Veratric Acid (10-100 μg/mL) has anti-inflammatory activity, protects HaCaT cells against UVB-mediated phototoxicity, increases S-phase cells, and prevents UVB-mediated apoptosis.
Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
In Vivo: Veratric acid (40 mg/kg, p.o., b.w.) significantly promotes ventricular function, reduces lipid peroxidation and increases antioxidants in l-NAME-induced hypertensive rats.
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文献和实验36 4.09 3.50 3.17 2.94 2.78 2.66 2.57 2.49 2.43 2.33 2.22 2.11 1.99 1.85 1.69 36 37 4.08 3.49 3.16 2.93 2.77 2.65 2.56 2.48 2.42 2.32 2.21 2.10 1.97 1.84 1.67 37 38 4.07 3.48 3.14 2.92 2.76 2.64 2.55 2.47 2.41 2.31 2.20 2.09 1.96 1.82 1.66 38
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