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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
4°C, protect from light
- 英文名：
Aristolochic acid I; TR 1736
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
313-67-7
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥330.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥100.0 |
| 规格： | 5 mg | 产品价格： | ￥190.0 |
| 规格： | 10 mg | 产品价格： | ￥300.0 |
| 规格： | 25 mg | 产品价格： | ￥500.0 |
| 规格： | 50 mg | 产品价格： | ￥850.0 |
| 规格： | 100 mg | 产品价格： | ￥1450.0 |
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Aristolochic acid A
CAS No. : 313-67-7
MCE 国际站：Aristolochic acid A
产品活性：Aristolochic acid A (Aristolochic acid I; TR 1736) 是植物提取物 Aristolochic acids 的主要成分，其存在于 Aristolochia 和 Asarum 草本植物中。Aristolochic acid A 显着降低激活蛋白1 (AP-1) 和 NF-κB 活性。Aristolochic acid A 降低人细胞中膀胱癌相关 BLCAP 基因表达。
研究领域：NF-κB
作用靶点：NF-κB
In Vitro: Aristolochic acid A (150, 200 μM, 24 hours) inhibits the cell viabilities of kidney cells HEK293 and HK-2.
Aristolochic acid A (100, 200 μM, 24 hours) causes a concentration-dependent decrease in bladder cancer-associated protein (BLCAP) mRNA levels in kidney cells (HEK 293 and HK-2) , and bladder cancer cell line (HT-1376).
Aristolochic acid A (100, 200 μM, 24 hours) weakens the BLCAP protein signals in a dose-dependent manner in both HEK293 and HT-1376 cells.
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文献和实验Molecular Modeling of Nucleic Acid Structure: Energy and Sampling
techniques as applied to nucleic acid systems is presented. This unit discusses methods used to treat energy and to sample representative configurations. Emphasis is placed on molecular mechanics and empirical force fields. Curr. Protoc. Nucleic Acid Chem
Molecular Modeling of Nucleic Acid Structure: Electrostatics and Solvation
of computer simulation techniques as applied to nucleic acid systems, ranging from simple in vacuo molecular modeling techniques to more complete all?atom molecular dynamics treatments that include an explicit representation of the environment. The third in a series
?cyanoethylthio group is effected by treatment with 2,4,6?triisopropybenzenesulfonyl chloride and triethylamine to give a 6?(2,4,6?triisopropylbenzenesulfonic acid) ester intermediate. Reaction of this key intermediate with 3?mercaptoproprionitrile
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