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- MedChemExpress(MCE)
- 美国
- HY-N0359
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Cynarine
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
30964-13-7
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥966.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥400.0 |
| 规格： | 5 mg | 产品价格： | ￥850.0 |
| 规格： | 10 mg | 产品价格： | ￥1400.0 |
| 规格： | 25 mg | 产品价格： | ￥2600.0 |
| 规格： | 50 mg | 产品价格： | ￥3900.0 |
| 规格： | 100 mg | 产品价格： | ￥5788.0 |
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Cynarin
CAS No. : 30964-13-7
MCE 国际站：Cynarin
产品活性：Cynarin是具有多种生物活性的抗窒息剂，具有抗氧化，抗组胺和抗病毒等活性。
研究领域：Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease | Anti-infection
作用靶点：Reactive Oxygen Species | Influenza Virus
In Vitro: Cynarin inhibits taste receptors, making water to be sweet. It has been shown to have some pharmacological properties including hypocholesterolemic, hepatoprotective, antiviral, antibacterial, and antihistamic effects. Cynarin has marked antioxidant, anticholinergic, reducing ability, radical-scavenging, and metal-binding activities. Cynarin demonstrates 87.72% inhibition of linoleic acid lipid peroxidation at 30 mg/mL concentration. Cynarin exhibits effective DMPD+, ABTS+, O2-, DPPH1, and H2O2 scavenging effects, reducing capabilities and Fe2+ chelating effects. IC50 and Ki of cynarin for acetylcholinesterase enzyme inhibition are 243.67nM and 39.34±13.88 nM, respectively. Cynarin is a potential immunosuppressant that blocks the interaction between the CD28 of T-cell receptor and CD80 of antigen presenting cells. Cynarin blocks about 87% of the CD28-dependent "signal 2" pathway of T-cell activation under the condition of one to one ratio of T-cell and B-cell. Cynarin binds to the "G-pocket" of CD28 and thus interrupts the site of interaction between CD28 and CD80.
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