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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
KP-103
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
164650-44-6
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥605.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥220.0 |
| 规格: | 5 mg | 产品价格: | ¥550.0 |
| 规格: | 10 mg | 产品价格: | ¥800.0 |
| 规格: | 50 mg | 产品价格: | ¥2200.0 |
| 规格: | 100 mg | 产品价格: | ¥3100.0 |
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Efinaconazole
CAS No. : 164650-44-6
MCE 国际站:Efinaconazole
产品活性:Efinaconazole (KP-103) 是一种三唑类抗真菌剂,以 MIC 值分别为 0.0039 μg/mL 和 0.00098 μg/mL 抑制 T. mentagrophytes SM-110 和 C. albicans ATCC 10231 菌株。Efinaconazole 对真菌病原体 (包括皮肤癣菌,念珠菌和马拉色菌属) 具有有效的体外活性。
研究领域:Anti-infection
作用靶点:Fungal
In Vivo: Topical Efinaconazole solution (0.25 to 1%) is dose-dependently effective in treating both dermatophytoses, for 10 guinea pigs with interdigital tinea pedis or tinea corporis is investigated. The follow up study performs on day-30 and day-9 posttreatment demonstrated that the relapse rates for 1% Efinaconazole-treated animals with tinea pedis and for those with tinea corporis are 20 and 30%, respectively. When a single dose of 1% Efinaconazole is applied to the back skin 48 hours before fungal inoculation, 9 of the 10 animals are protected from the dermatophytosis, suggesting that active Efinaconazole is retained in skin tissue for at least 48 hours after dosing.
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