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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
Ravtansine
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
796073-69-3
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥918.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥409.0 |
| 规格: | 5 mg | 产品价格: | ¥700.0 |
| 规格: | 10 mg | 产品价格: | ¥1070.0 |
| 规格: | 25 mg | 产品价格: | ¥1920.0 |
| 规格: | 50 mg | 产品价格: | ¥2880.0 |
| 规格: | 100 mg | 产品价格: | ¥4320.0 |
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DM4
CAS No. : 796073-69-3
MCE 国际站:DM4
产品活性:DM4 是抑制细胞分裂的抗微管蛋白剂。DM4 可用于制备抗体活性分子偶联物。
研究领域:Cell Cycle/DNA Damage | Cytoskeleton | Antibody-drug Conjugate/ADC Related
作用靶点:Microtubule/Tubulin | ADC Cytotoxin
In Vitro: DM4, a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death.
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