BRD 4354,315698-07-8

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BRD 4354

CAS No. : 315698-07-8

MCE 国际站：BRD 4354

产品活性：BRD 4354 是 HDAC5 和 HDAC9 的抑制剂，其 IC₅₀ 值分别为 0.85，1.88 μM。

研究领域：Cell Cycle/DNA Damage  |  Epigenetics

作用靶点：HDAC

In Vitro: BRD 4354 is a moderately potent inhibitor of HDAC5 and HDAC9, with BRD4354 having half-maximum inhibitory concentrations (IC₅₀) of 0.85 μM and 1.88 μM, respectively. BRD 4354 also inhibits HDACs 4, 6, 7, and 8 at higher concentrations (3.88-13.8 μM) but demonstrates less of an inhibitory effect on other class I HDACs 1, 2, and 3 (IC₅₀>40 μM) .

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