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VU6012962
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Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
货期:1-2天
MedChemExpress LLC
2313526-86-0
10 mM * 1 mL/5 mg/10 mg/50 mg
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
CAS No. : 2313526-86-0
MCE 国际站:VU6012962
产品活性:VU6012962 是一种口服生物可利用的,可渗透 CNS 的,代谢型谷氨酸受体 7 阴性变构调节剂 (mGlu7 NAM),IC50 为 347 nM。
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:mGluR
In Vitro: VU6012962 is highly selective for mGlu7 versus the other seven mGlu receptor subtypes.
In Vivo: VU6012962 (1-10 mg/kg; i.p. injection; 60 minutes prior to testing) decreases anxiety in the elevated zero maze (EZM) assay in mice.
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