SNT-207858,1104080-42-3

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

SNT-207858

CAS No. : 1104080-42-3

MCE 国际站：SNT-207858

产品活性：SNT-207858 是一种选择性，可渗透血脑屏障的，有口服活性的黑皮质素 (melanocortin; MC-4) 受体拮抗剂，SNT-207858 抑制与 MC-4 受体结合，IC₅₀ 为 22 nM。SNT-207858 抑制 MC-4 活性，IC₅₀ 为 11 nM。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：Melanocortin Receptor

In Vitro: SNT207858 binds to the MC-4 receptor with an affinity of 22 nM and shows a 170-fold selectivity vs. MC-3 and a 40-fold selectivity vs. MC-5.

In Vivo: SNT207858 (30 mg/kg; oral administration; once daily; 15 days) significantly reduces the tumor induced weight loss in mice.

相关产品：α-MSH  |  SHU 9119  |  Melanotan I  |  Bremelanotide Acetate  |  Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA  |  BMS-470539 dihydrochloride  |  THIQ  |  Nonapeptide-1 acetate salt  |  JNJ-10229570  |  PF-00446687  |  HS024 TFA  |  β-Melanocyte Stimulating Hormone (MSH), human TFA  |  ACTH (1-17) (TFA)  |  RO27-3225 TFA  |  SNT-207707  |  ACTH (11-24)  |  Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA)  |  HS014 TFA  |  MK-0493  |  SNT-207858 free base  |  Dersimelagon  |  ML00253764  |  MSG606  |  PG-931  |  γ-1-Melanocyte Stimulating Hormone (MSH), amide  |  Fenoprofen  |  [D-Trp8]-γ-MSH  |  γ1-MSH

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds