VU 0365114,1208222-39-2

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VU 0365114

CAS No. : 1208222-39-2

MCE 国际站：VU 0365114

产品活性：VU 0365114 是选择性的 mAChR M₅ 的正变构调节剂，其 EC₅₀ 值为2.7 μM，对 M1, M2, M3 and M4 受体的 EC₅₀ >30 μM。VU 0365114 增加人 β 细胞中 ACh 刺激的胰岛素分泌。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：mAChR

In Vitro: VU 0365114 (10 μM) increases insulin secretion stimulated by ACh in human β-cells.
VU 0365114 (10 μM) does not alter somatostatin secretion stimulated by ACh in human β-cells.

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