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- 保存条件：
4°C, sealed storage, away from moisture
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
146709-78-6
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1254.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1200.0 |
| 规格： | 10 mg | 产品价格： | ￥1800.0 |
| 规格： | 25 mg | 产品价格： | ￥2520.0 |
| 规格： | 50 mg | 产品价格： | ￥3528.0 |
| 规格： | 100 mg | 产品价格： | ￥4939.0 |
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ZD 7155(hydrochloride)
CAS No. : 146709-78-6
MCE 国际站：ZD 7155(hydrochloride)
产品活性：ZD 7155 hydrochloride是血管紧张素II受体1型 (AT1 receptor) 拮抗剂。
研究领域：GPCR/G Protein
作用靶点：Angiotensin Receptor
In Vivo: In conscious SD rats, ZD 7155 and losartan behave as competitive antagonists and the pressor response curve to angiotensin II is shifted to the right. Experiments in conscious SD rats also show that ZD 7155 is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response (240 ng/kg; 10 min infusion). In addition, experiments with conscious rats demonstrate that ZD 7155 could suppress the angiotensin II-induced pressor response for approximately 24 h when ZD 7155 is administered intravenously in a 1.082 μmol/kg bolus dose and angiotensin II is given at 240 ng/kg (in a 10-min infusion). Experiments in conscious SHRs using ZD 7155 (1.082 mumol/kg) and losartan (6.495 mumol/kg) as intravenous boluses indicate that both ZD 7155 and the reference compound losartan exhibit a significant antihypertensive effect.
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文献和实验DTIAJMAEmwASYgEIJsPChUNw8GBNgAkyACTABJsDCB78HmAATYAJMgAkwAYUSYOFDobh5MCbABJgAE2ACTICFD34PMAEmwASYABNgAgolwMKHQnHzYEyACTABJsAEmAALH/weYAJMgAkwASbABBRKgIUPheLmwZgAE2ACTIAJMAEWPvg9wASYABNgAkyACSiUAAsfCsXNgzEBJsAEmAATYAIsfPB7gAkwASbABJgAE1AoARY+FIqbB2MCTIAJMAEmwARY+OD
Surface Plasmon Resonance for Measurements of Biological Interest
: N ‐ethyl‐N′‐[(dimethylamino) propyl] carbodiimide hydrochloride (EDC) N ‐hydroxysuccinimide (NHS)
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