- ￥560 - 3928
- MedChemExpress(MCE)
- 美国
- HY-100343
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1449277-10-4
- 规格：
1 mg/5 mg/10 mg/25 mg/50 mg
| 规格： | 1 mg | 产品价格： | ￥560.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥980.0 |
| 规格： | 10 mg | 产品价格： | ￥1480.0 |
| 规格： | 25 mg | 产品价格： | ￥2380.0 |
| 规格： | 50 mg | 产品价格： | ￥3928.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
GNE-495
CAS No. : 1449277-10-4
MCE 国际站：GNE-495
产品活性：GNE-495 是有效，选择性的 MAP4K4 抑制剂，IC50 值3.7 nM。
研究领域：MAPK/ERK Pathway
作用靶点：MAP4K
In Vitro: GNE-495 is a potent and selective MAP4K4 inhibitor with efficacy in retinal angiogenesis. GNE-495 shows the best balance of MAP4K4 inhibition, permeability, microsomal stability, and cellular potency.
In Vivo: GNE-495 is administered intraperitoneally to neonatal mouse pups at high doses: 25 and 50 mg/kg. GNE-495 shows good in vivo profile in all species tested, with low clearances, moderate terminal half-lives, and reasonable oral exposure levels (F=37-47%).
相关产品：Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | MAPK Compound Library | Anti-Cancer Compound Library | Oxygen Sensing Compound Library | Anti-Obesity Compound Library | Targeted Diversity Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | Serine/Threonine Kinase Inhibitor Library | NCB-0846 | DMX-5804 | HPK1-IN-3 | GNE-1858 | HPK1-IN-7 | NG25 | PF-06260933 | KY-05009 | MAP4K4-IN-3 | HPK1-IN-32 | HPK1-IN-4 | GNE 220 hydrochloride | HPK1-IN-8 | SS47 TFA | TAK1/MAP4K2 inhibitor 1 | DB1113 | HPK1-IN-26 | TL4-12 | ZYF0033 | HPK1-IN-34 | HPK1-IN-19 | DS21150768 | FLT3/ITD-IN-4 | GNE-6893 | HPK1 antagonist-1 | HPK1-IN-10 | HPK1-IN-11 | HPK1-IN-12
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
