COX-2-IN-2,134729-13-8

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COX-2-IN-2

CAS No. : 134729-13-8

MCE 国际站：COX-2-IN-2

产品活性：COX-2-IN-2 是选择性的，诱导型的 COX2 抑制剂，IC₅₀ 值为0.24 μM。COX-2-IN-2 是具有抗炎和止痛活性的抗炎物。

研究领域：Immunology/Inflammation

作用靶点：COX

In Vitro: COX-2-IN-2 shows no COX-1 inhibition even at 100μM.

In Vivo: COX-2-IN-2 has oral ED₅₀ values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED₃₀ value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity.

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