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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
CVT 303 dihydrochloride; RS 43285
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
95635-56-6
- 规格：
10 mM * 1 mL/100 mg/200 mg/500 mg/1 g/5 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥660.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥600.0 |
| 规格： | 200 mg | 产品价格： | ￥960.0 |
| 规格： | 500 mg | 产品价格： | ￥1600.0 |
| 规格： | 1 g | 产品价格： | ￥2000.0 |
| 规格： | 5 g | 产品价格： | ￥6000.0 |
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Ranolazine dihydrochloride
CAS No. : 95635-56-6
MCE 国际站：Ranolazine dihydrochloride
产品活性：Ranolazine dihydrochloride (CVT 303 dihydrochloride) 是一种抗心绞痛和抗缺血剂，可通过抑制内向钠电流的后期作用 (对 INa 和 IKr 的 IC50 值分别为 6 μM 和 12 μM) 来发挥功效，而不会影响心率或血压。Ranolazine dihydrochloride 还是脂肪酸氧化的部分抑制剂。
研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling | Autophagy
作用靶点：Calcium Channel | Sodium Channel | Autophagy
In Vivo: Ranolazine (Bolus injection 10 mg/kg and infusion 9.6 mg/kg/h; bolus injection; for 145 minutes; male Wistar rats) treatment significantly reduces infarct size and cardiac troponin T release in rats subjected to left anterior descending coronary artery occlusion-reperfusion.
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