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Desethyl KBT-3022
CAS No. : 101001-72-3
MCE 国际站：Desethyl KBT-3022
产品活性：Desethyl KBT-3022是新型抗血小板活性分子KBT-3022的主要活性代谢物。
研究领域：Metabolic Enzyme/Protease
作用靶点：Thrombin
In Vitro: Pretreatment with desethyl KBT-3022 0.1, 0.3 and 1 mg/kg, i.v. prolongs the time required to achieve thrombotic occlusion in the femoral artery and inhibits collagen-induced platelet aggregation in whole blood ex vivo, each in a dose-dependent manner. Desethyl KBT-3022 inhibits the thrombin-induced aggregation of washed platelets in a concentration-dependent manner 1–40 μM.
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文献和实验On-chip Isotachophoresis for Separation of Ions and Purification of Nucleic Acids
(8), 3022 (2009). 9. Schoch, R.B., Ronaghi, M., & Santiago, J.G. Rapid and selective extraction, isolation, preconcentration, and quantitation of small RNAs from cell lysate using on-chip isotachophoresis. Lab Chip. 9 (15), 2145 (2009). 10.
. Milenkovic, V.M., Langmann, T., Schreiber, R., Kunzelmann, K., and Weber, B.H. 2008. Molecular evolution and functional divergence of the bestrophin protein family. BMC Evol. Biol. 8:72
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