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- 2025年12月05日
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Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名：
RnADA
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
1 mg
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Adenosine deaminase (RnADA)
CAS No. : 9026-93-1
MCE 国际站：Adenosine deaminase (RnADA)
产品活性：Adenosine deaminase (RnADA) 是一种酶，可以对腺苷和 2'-脱氧腺苷进行不可逆的脱氨基作用，分别转化为肌苷和 2'-脱氧肌苷。
研究领域：Metabolic Enzyme/Protease
作用靶点：Adenosine Deaminase
In Vitro: Adenosine deaminase (RnADA) catalyzes the irreversible deamination of adenosine and 2′-deoxyadenosine to inosine and 2′-deoxyinosine, respectively. Adenosine deaminase (RnADA) is implicated in purine metabolism and distributed in most mammalian tissues. Genetic Adenosine deaminase deficiency results in lymphopenia and severe combined immunodeficiency disease by decreasing the differentiation and maturation of lymphoid cells. Adenosine deaminase (RnADA) is a signaling molecule related to the activation of T lympho-cytes, making it a useful inflammation marker, especially for menin-gitis and tuberculous pleuritis.
This product is derived fro M microbial recombinant protein, is stable at pH 7.0-9.0, and has a molecular weight of 42 kDa (SDS-PAGE).
Solution preparation
Reconstitute with pure water containing 20% ??glycerol, aliquot according to dosage and freeze at 20℃. It can be stored for 2 years. Try to avoid repeated freezing and thawing.pH7 0 9.0 means the product is stable.
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文献和实验腺苷脱氨酶 adenosine deaminase 催化腺苷的氨基水解脱氨生成次黄核苷和氨反应的酶。 EC 3． 5． 4． 4。主要存在于肝脏和肌肉，而其他动物器官也广泛存在。另外，也存在于曲霉中。来自前者的酶特异性强，对腺苷和脱氧腺苷以外的核酸及其分解物不起作用，但来自后者的酶（高峰淀粉酶）是非特异性的，可对 5′－ AMP、 ADP、 ATP、嘧啶二核苷酸等起脱氨作用。
Methods for the Analysis of Adenosine-to-Inosine Editing in RNA
In this work we describe methods for the analysis of RNAs that have been edited by the double-strand RNA-specific adenosine deaminase, ADAR. These RNAs contain inosine residues that can be detected and quantified by a variety
Characterization of P1 (Adenosine) Purinoceptors
) A 1 assay buffer: 50 mM Tris·Cl, pH 7.4 at 23°C ( appendix 2A ), 4°C Adenosine deaminase (type III; Boehringer Mannheim
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