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- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Trimethoprim 3-N-oxide
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- 规格：
1 mg/5 mg
| 规格： | 1 mg | 产品价格： | ￥1300.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥3900.0 |
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Trimethoprim 3-oxide
CAS No. : 27653-67-4
MCE 国际站：Trimethoprim 3-oxide
产品活性：Trimethoprim 3-oxide 为一种三甲氧苄二氨嘧啶的初级代谢物。
研究领域：Metabolic Enzyme/Protease
作用靶点：Drug Metabolite
In Vitro: Trimethoprim 3-oxide is the primary metabolite of trimethoprim.
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation.
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文献和实验Resistance to Tetracyclines, Macrolides, Trimethoprim and Sulfonamides
Tetracyclines are antimicrobial agents that interact with bacterial ribosomes and block protein synthesis. They have activity against a wide range of gram positive, gram-negative, anaerobic and aerobic bacteria, cell-wall free myco plasmas
质疑｜NEJM 疑似误用「尿结晶」图片，医学顶刊也犯低级错误？！
2021 年 3 月 18 日，世界著名的医学四大期刊之一 The New England Journal of Medicine 杂志刊登了一篇文章 Sulfonamide Crystals [1]。作者是泰国曼谷 Mahidol 大学的 Kanin Thammavaranucupt 博士和 Ittikorn Spanuchart 博士，英文正文如下:图源：The New England Journal of Medicine文中所述一位 42 岁患者接受了 trimethoprim
)5.SpermidineReduces non-specific reactions between the polymerase and DNA.· Tris-HCl: 10 mM - 67 mM, pH 8.2 - 9.0· KCl: 25 mM - 50 mM· MgCl2: 1.5 - 5.0 mM· Gelatin: 0.01% - 0.1% (w/v)· Non-ionic detergents· Tween 20: 0.05% (v/v)· Triton-X-100: 0.01% (v/v)· Tetramethyl
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