TBK1/IKKε-IN-1,2058264-32-5

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

TBK1/IKKε-IN-1

CAS No. : 2058264-32-5

MCE 国际站：TBK1/IKKε-IN-1

产品活性：TBK1/IKKε-IN-1 是一种双重 TBK1 和 IKKε 抑制剂，IC₅₀s 值 <100 nM。详细信息请参考专利文献 US20160376283 A1 中 Example 60 中的化合物 274。

研究领域：NF-κB

作用靶点：IKK

In Vitro: IKKε and TBK1 are serine/threonine kinases which are highly homologous to one another and other IkB kinases (IKK-α and IKK-β). The two kinases play an integral role in the innate immune system. Double-stranded RNA viruses are recognised by the Toll-like receptors 3 and 4 and the RNA helicases RIG-I and MDA-5 and result in activation of the TRIF-TBK1/IKKε-IRF3 signalling cascade, which results in a type I interferon response.

相关产品：BAY 11-7082  |  Resveratrol  |  BX795  |  GSK8612  |  TPCA-1  |  Amlexanox  |  MRT67307  |  IMD-0354  |  IKK 16  |  BMS-345541  |  MLN120B  |  ACHP Hydrochloride  |  BAY-985  |  HOIPIN-1  |  PS-1145  |  TBK1/IKKε-IN-5  |  Vinpocetine  |  BI605906  |  Tizoxanide  |  SC-514  |  GS143  |  INH14  |  BAY32-5915  |  NF-κB-IN-1  |  LY2409881 trihydrochloride  |  Malachite green hemioxalate  |  Plantainoside D  |  TBK1/IKKε-IN-2

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds