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货期:1-2天
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MedChemExpress LLC
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1 mg/5 mg/10 mg/25 mg/50 mg/100 mg/200 mg
| 规格: | 1 mg | 产品价格: | ¥248.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥540.0 |
| 规格: | 10 mg | 产品价格: | ¥760.0 |
| 规格: | 25 mg | 产品价格: | ¥1520.0 |
| 规格: | 50 mg | 产品价格: | ¥2200.0 |
| 规格: | 100 mg | 产品价格: | ¥3500.0 |
| 规格: | 200 mg | 产品价格: | ¥5275.0 |
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IQ 1
CAS No. : 331001-62-8
MCE 国际站:IQ 1
产品活性:IQ 1是一种 Wnt/β-catenin/CBP 信号维持剂。IQ 1 通过增强 β-catenin/CBP 介导的转录并防止转换到 β-catenin/p300 介导的转录来维持 Wnt/β-catenin 驱动的小鼠胚胎干细胞 (ESCs) 长期扩增并防止自发分化。IQ-1 通过与 PR72/130 的相互作用调节 Wnt 信号传导。IQ 1 可用于 ESCs 扩增的研究。
研究领域:Stem Cell/Wnt
作用靶点:Wnt
In Vitro: IQ-1 (1.10, 3.48, 11.04 mM; 7 days) maintains the undifferentiated state of ESCs.
IQ-1 (0.28, 1.10, 2.76, 11.04 mM; 21 h) maintains murine ESC self-renewal independently of LIF.
IQ-1 Binds the PR72/130 Subunit of the Serine/Threonine Phosphatase PP2A in P19 cells.
IQ-1 (10 µM; 24 h) modulates Wnt signaling via interaction with PR72/130 in P19 cells.
IQ-1 (10 µM; 24 h) indirectly decreases the phosphorylation of p300 Ser-89 and Thereby the β-Catenin/p300 interaction.
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文献和实验CD62E/CD62L/CD62P 分子 CD62E 常用单克隆抗体或代号: 3B7,4D1O;(E- selectin,ELAM- 1) 主要表达细胞: En [AS] 分子质量(kDa)和结构: gp110(C- lectin SF)结合白细胞ELS- 1 功 能: 粘附L- selectin,中性粒细胞通过结合CD15s结合到En CD62L 常用单克隆抗体或代号: Leu8,FMC46;(L-
DNA Extraction Promega DNA-IQ System Database Protocol
or pair of tweezers Container of sterile 1.5 mL microcentrifuge tubes DNA-IQ magnetic stand Biohazard waste container Set of micropipettors One small beaker for waste Calculator Timer Ultra-fine point sharpie
DNA Extraction Promega DNA-IQ System Database Protocol
or pair of tweezers Container of sterile 1.5 mL microcentrifuge tubes DNA-IQ magnetic stand Biohazard waste container Set of micropipettors One small beaker for waste Calculator Timer Ultra-fine point sharpie
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