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207277-66-5
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NNC45-0781
CAS No. : 207277-66-5
MCE 国际站：NNC45-0781
产品活性：NNC45-0781 是一种组织选择性的雌激素 (estrogen) 部分激动剂。
研究领域：Vitamin D Related/Nuclear Receptor
作用靶点：Estrogen Receptor/ERR
In Vivo: NNC45-0781 (NNC 45-0781) shows that it is a very promising tissue-selective estrogen agonist. Total serum cholesterol is significantly increased in the vehicle-treated group as compared to the sham animals. All of the animals receiving NNC45-0781 at doses of 10 nmol/g or higher, has significantly lower levels of total serum cholesterol as compared to the vehicle treated group.
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文献和实验细菌RNA的提取--ISOLATION OF RNA FROM BACTEROIDS
for gels.formaldehyde gels:see manualrun in cold room O/N at 15 V in minigel; unitblot directly to nylon-66 membranesdeionizing formamide - use columns, do not add resin directly to formamide.BLOTTING FORMALDEHYDE GELSBlot 15-45 min with 50 mM NaOH
1.90134±2.30(106-146)4.66±0.405.30±0.50(4.00-5.90)96.7±1.1993.8±1.20(85.7-112)37.3±2.2039.1±2.30(32.7-44.1)5.29±0.966.04±1.10(3.40-8.24)9.52±0.9810.4±0.92(7.40-12.0)2.54±0.222.20±0.14(1.90-3.50)狗0.25±0.110.21±0.10(0.00-0.50)211±32.0150±17.0(137-275)1.35±
表 百分率 0 1 2 3 4 5 6 7 8 9 0 ― 2.67 2.95 3.12 3.25 3.36 3.45 3.52 3.59 3.66 10 3.72 3.77 3.83 3.87 3.92 3.96 4.01 4.05 4.08 4.12 20 4.16 4.19 4.23 4.26 4.29 4.33 4.36 4.39 4.42 4.45 30 4.48 4.50 4.53 4.56 4.59 4.61 4.64 4.67 4.69 4.72 40 4.75 4.77
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