AD 0261,145600-69-7

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AD 0261

CAS No. : 145600-69-7

MCE 国际站：AD 0261

产品活性：AD 0261是一种自由基清除剂，能够有效抑制脂质过氧化物和超氧化物阴离子的产生。

研究领域：Immunology/Inflammation  |  NF-κB  |  Metabolic Enzyme/Protease

作用靶点：Reactive Oxygen Species

In Vitro: AD 0261 displays strong inhibitory action on the generation of lipid peroxides (IC₅₀=0.022 μM) and superoxide anions (IC₅₀= 0.9-4.0 μM). AD 0261 inhibits cytokine release and/or production from PHA-P-stimulated lymphocytes in a dose-dependent manner. AD 0261 inhibits all parameters which are indicative of lymphocyte activation with 50% inhibition being achieved in a range of 1-10 μM. AD 0261 suppresses ornithine decarboxylase activity, the IC₅₀ value being around 1.0 μM.

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