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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
polypeptide, sealed storage, away from moisture and light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
1 mg/5 mg/10 mg
| 规格: | 1 mg | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1180.0 |
| 规格: | 10 mg | 产品价格: | ¥1770.0 |
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ATWLPPR Peptide TFA
MCE 国际站:ATWLPPR Peptide TFA
产品活性:ATWLPPR Peptide TFA 是一种选择性的 neuropilin-1 (NRP-1) 抑制剂,能够抑制 VEGF165 与 NRP-1 结合,可用于血管生成的研究。ATWLPPR Peptide TFA 能够减轻糖尿病引起的早期视网膜损伤。
作用靶点:Complement System
In Vitro: ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1 by 82% at 100 μM.
In Vivo: ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes.
ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF and ICAM-1) in the retina.
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文献和实验二个以上的α -氨基酸以肽键连接起来而形成的化合物。根据构成氨基酸的数目 2、 3、 4……叫做二肽( dipeptide)、三肽、四肽……。大体上由 10以下的肽键形成的肽总称为寡肽 ( Oligopeptide),由多数肽键构成的肽总称为多肽。每个肽按照构成它的氨基酸的名称,从具有游离α -氨基的末端氨基酸依次命名。例如 称为甘氨酰丙氨酸的二肽。蛋白质是由一条或几条长链状多肽构成的。象谷胱甘肽和肌肽那样的低
Two dimensional peptide mapping
This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol
Peptide Bioinformatics- Peptide Classification Using Peptide Machines
Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research subjects, such as functional site prediction, protein structure identification, and protein function recognition
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