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- 详细信息
- 技术资料
- 保存条件:
polypeptide, sealed storage, away from moisture and light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
1 mg/5 mg/10 mg
| 规格: | 1 mg | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥1180.0 |
| 规格: | 10 mg | 产品价格: | ¥1770.0 |
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ATWLPPR Peptide TFA
MCE 国际站:ATWLPPR Peptide TFA
产品活性:ATWLPPR Peptide TFA 是一种选择性的 neuropilin-1 (NRP-1) 抑制剂,能够抑制 VEGF165 与 NRP-1 结合,可用于血管生成的研究。ATWLPPR Peptide TFA 能够减轻糖尿病引起的早期视网膜损伤。
作用靶点:Complement System
In Vitro: ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1 by 82% at 100 μM.
In Vivo: ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes.
ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF and ICAM-1) in the retina.
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