Dimetacrine

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Dimetacrine

CAS No. : 4757-55-5

MCE 国际站：Dimetacrine

产品活性：Dimetacrine 是一种有用的抗抑作用，可用于各种类型的抑郁症的研究。

研究领域：Others

作用靶点：Others

In Vivo: Dimetacrine is a useful antidepressant which can be used for the treatment of various types of depression. Dimetacrine in the highest concentration, 10 μM, decreases the contractile force to 36.5±9.1%. Dimetacrine, 0.3 μM, causes no statistically significant decline in contractile force from the controls. Tachycardia is observed after the administration of Dimetacrine, 1 to 3 mg/kg i.v., and the maximum response is obtained in dose of 3 mg/kg i.v.. The administration of Dimetacrine, 30 mg/kg i.v., causes an abrupt fall in blood pressure with tachycardia or bradycardia followed by cardiac arrest. Respiratory rate increases 40 min after the onset of infusion of Dimetacrine. Arterial blood pressure falls 50 min after the onset of infusion of Dimetacrine.

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