重组人钙连蛋白(Calnexin)北京厂家

特别提示：包括重组人钙连蛋白(Calnexin)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人钙连蛋白(Calnexin)
英文名称：Recombinant Human Calnexin
产品货号：JN0632
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His21-Pro481在C端含有His标签。

Calnexin质量控制：＞95%(还原性SDS-PAGE)

Calnexin制剂：液体

Calnexin保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Calnexin：
Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.

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