17-OH-progesterone (17-OHP) is the most suitable biochemical marker for the diagnosis of congenital adrenal hyperplasia (CAH). CAH has a prevalence of 1-20 in 10,000 children and it is one of the most frequent inborn endocrine disorders.
The most common form of CAH is due to a deficiency of the enzyme 21-hydroxylase. Depending on the severity of the enzymatic defect, the CAH related symptoms vary from salt lost syndrome in infants to hirsutism and/or infertility that manifest during puberty or adulthood (late-onset CAH).
ADVANTAGES OF THE IBL INTERNATIONAL 17-OHP ELISA • Excellent analytical characteristics
• For the 17-OHP serum ELISA age-dependent reference ranges for children
• Easy 17-OHP monitoring in saliva
• Serum, plasma ELISA: EU: CE
• Easy to adapt to automated instruments