- ￥463 - 6880
- TargetMol
- 美国
- T5091
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
FM-381
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2226521-65-7
- 规格：
100 mg/1 mg/50 mg/1 mL/5 mg/25 mg/10 mg
| 规格： | 100 mg | 产品价格： | ￥6880.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥463.0 |
| 规格： | 50 mg | 产品价格： | ￥4920.0 |
| 规格： | 1 mL | 产品价格： | ￥1280.0 |
| 规格： | 5 mg | 产品价格： | ￥1160.0 |
| 规格： | 25 mg | 产品价格： | ￥3390.0 |
| 规格： | 10 mg | 产品价格： | ￥1660.0 |
Product Introduction
Bioactivity
英文名:FM-381
描述:FM381 is a potent covalent reversible inhibitor of JAK3. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.
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文献和实验Investigating G Protein-Coupled Receptor Endocytosis and Trafficking by TIR-FM
, some of which occur on a rapid timescale similar to that of functional signaling itself. Here, we describe and discuss an optical imaging approach, based on evanescent field or total internal reflection-fluorescence microscopy (TIR-FM), to investigate receptor
and describe two advanced protocols that make use of the membrane binding dye FM 1-43, enabling to probe deep into the mechanisms of synaptic vesicle function and dynamics at the Drosophila third instar larval neuromuscular junction.
of the unique fluorescent FM dyes allowed the monitoring of fast synaptic vesicle exo-endocytic cycling during live imaging sessions and after photoconversion of FM dyes into an electron-dense diaminobenzidine polymer synaptic vesicle cycling can be studied
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