- ￥1350 - 3000
- Proteintech
- 27823-1-AP
- 2025年10月13日
- WB, IHC, ELISA
- Rabbit
- Human, Pig
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human LAMP2 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Pig
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IHC, ELISA
- 靶点：
CD107b / LAMP2
- 抗体英文名：
CD107b / LAMP2 Polyclonal antibody
- 抗体名：
CD107b / LAMP2 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | HepG2 cells, Jurkat cells, pig liver tissue, human placenta tissue |
| Positive IHC detected in | human liver tissue, human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
27823-1-AP targets CD107b / LAMP2 in WB, IHC, IF, ELISA applications and shows reactivity with Human, Pig samples.
| 经测试应用 | WB, IHC, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | Human, Pig |
| 文献引用反应性 | human, pig, monkey |
| 免疫原 |
CatNo: Ag27183 Product name: Recombinant human LAMP2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 29-230 aa of BC002965 Sequence: LELNLTDSENATCLYAKWQMNFTVRYETTNKTYKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGND |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | lysosomal-associated membrane protein 2 |
| 别名 | CD107b, Cell and organelle markers, LAMP 2, LAMP2, LAMPB, LGP110, Lysosome Marker |
| 计算分子量 | 45 kDa |
| 观测分子量 | 120 kDa |
| GenBank蛋白编号 | BC002965 |
| 基因名称 | LAMP2 |
| Gene ID (NCBI) | 3920 |
| ENSEMBL Gene ID | ENSG00000005893 |
| RRID | AB_2880983 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P13473 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides.
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- 作者
- 内容
- 询问日期
文献和实验| Species | Application | Title |
|---|---|---|
| human | WB | Nature 7-Dehydrocholesterol dictates ferroptosis sensitivityAuthors - Yaxu Li |
| human | WB | J Extracell Vesicles Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.Authors - Xiaoyu Yu |
| WB | Autophagy USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.Authors - Xibao Zhao | |
| pig | IF | Autophagy Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell cultureAuthors - Tao Wang |
| human | WB | Oxid Med Cell Longev Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration.Authors - Liang Kang |
| pig | WB | J Anim Sci Biotechnol Glyphosate exposure deteriorates oocyte meiotic maturation via induction of organelle dysfunctions in pigs.Authors - Chunhua Xing |
细胞激活；④通过转基因表达CD40L的成纤维细胞。也能刺激B细胞；⑤CD40或CD40L基因敲除的小鼠，抗体产生形成的缺陷类似人类的X性联高IgM血症，患者只产生了IgM，而无其他类别的抗体，也无生发中心，抗感染能力明显下降。 CD40与其配体CD401。的结合，导致CD40分子的寡聚化，使胞质中的TNF受体相关因子(TNF receptor-associ-atedfactor，TRAF)与CD40的胞内结构域结合。TRAF参与启动的酶催化级联反应，最终导致转录因子NFκB和AP-1等活化。
Rapid Inactivation of Proteins by Knocksideways
21967 (B ). The cells were treated either with 200 nM rapamycin for 10 min (A) or with 5 µM AP21967 for 10 min, fixed, and labeled for AP‐2‐FKBP. The cells in (A) were double labeled for the HA tag; the cells in (B) were not double labeled
LINEAGE ANALYSIS USING RETROVIRAL VECTORS
], that include degenerate oligonucleotides with a theoretical complexity of 1.7 x 107. Studies in the developing nervous system of the chick have been successfully completed using CHAPOL [47, 48]. A summary of the production of CHAPOL and BOLAP (an oligo
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