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Thymosin beta 4 多克隆抗体 19850-1-

AP
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  • ￥1350 - 3000
  • Proteintech已认证
  • 19850-1-AP
  • 2025年10月13日
  • IHC, IF-P, IP, ELISA
  • Rabbit
  • human, mouse, rat
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human TMSB4X protein

    • 亚型：

      IgG

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Polyclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human, mouse, rat

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Rabbit

    • 应用范围：

      IHC, IF-P, IP, ELISA

    • 靶点：

      Thymosin beta 4

    • 抗体英文名：

      Thymosin beta 4 Polyclonal antibody

    • 抗体名：

      Thymosin beta 4 Polyclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive IP detected inmouse skeletal muscle tissue
    Positive IHC detected inmouse skeletal muscle tissue, mouse colon tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF-P detected inmouse heart tissue

    推荐稀释比

    应用推荐稀释比
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    Immunohistochemistry (IHC)IHC : 1:50-1:500
    Immunofluorescence (IF)-PIF-P : 1:400-1:1600
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    19850-1-AP targets Thymosin beta 4 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

    经测试应用 IHC, IF-P, IP, ELISA
    文献引用应用WB, IHC, IF
    经测试反应性 human, mouse, rat
    文献引用反应性human, mouse, chicken
    免疫原

    CatNo: Ag13914

    Product name: Recombinant human TMSB4X protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-63 aa of BC001631

    Sequence: AQTRLRSYSCASLRFSSATMSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 thymosin beta 4, X-linked
    别名 TMSB4X, TB4X, T beta-4, T beta 4, PTMB4
    计算分子量 63 aa, 7 kDa
    观测分子量 5 kDa
    GenBank蛋白编号BC001631
    基因名称 Thymosin beta 4
    Gene ID (NCBI) 7114
    RRIDAB_10642437
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP62328
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Thymosin beta 4 (Tβ4), encoded by TMSB4X gene, is an actin sequestering protein which plays an important role in the organization of the cytoskeleton. Numerous studies have demonstrated the effects of Tβ4 on cell migration, proliferation, apoptosis and inflammation after exogenous treatment (PMID: 22652458). Recently, novel findings provided compelling evidence that Tβ4 played a key role in facilitating tumor metastasis and angiogenesis. It has been found that Tβ4 expressed increasingly in a number of metastatic tumors, thus providing a potential target of opportunity for cancer management, especially for cancer metastasis therapy (PMID: 22856429).

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    • 作者
    • 内容
    • 询问日期
    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle
    humanWB,IF

    Adv Sci (Weinh)

    Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing

    Authors - Youjun Ding
    humanIHC

    Nat Commun

    Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma

    Authors - Weilin Pu
    humanIF

    Front Med

    Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell RNA-seq analysis

    Authors - Weiwei Xian
    chickenIF

    Elife

    Single-cell proteomics reveals changes in expression during hair-cell development.

    Authors - Ying Zhu
    humanWB

    J Mol Cell Biol

    Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

    Authors - Zhou Yizhuo Y
    • KD Validated
    mouseWB

    Haematologica

    Thymosin β4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets.

    Authors - Inga Scheller
    • KO Validated
    相关实验

    • Western Blot(免疫印迹法)步骤

      10X TBS：24.2 g Trisbase, 80 g NaCl；用1N HCl调pH为 7.6 7. 甲醇 8. TBS/T缓冲液：1X TBS, 0.1% Tween-20 9. 封闭缓冲液(TBS/T)：1X TBS,0.1% Tween-20加5% w/v脱脂奶粉或BSA 10. 一抗的稀释：1X TBS,0.1% Tween-20 加 5% BSA ( 多抗) 或 5%脱脂奶粉( 单抗)。Note： 一般来说，BSA被推荐用于多克隆抗体

    • [资源] 所有的看家基因(housekeeping genes)列表+引物设计服务

      sapiens synaptogyrin 2 (SYNGR2), mRNA 1414 NM_001127 Homo sapiens adaptor-related protein complex 1, beta 1 subunit (AP1B1), transcript variant 1, mRNA 873 NM_002107 Homo sapiens H3 histone, family 3A (H3F3A), mRNA 9328 NM_003899 Homo sapiens Rho

    • Western Blot杂交膜转移与免疫显色

      10X TBS：24.2 g Trisbase, 80 g NaCl;用1N HCl调pH为 7.6 7. 甲醇 8. TBS/T缓冲液：1X TBS, 0.1% Tween-20 9. 封闭缓冲液(TBS/T)：1X TBS,0.1% Tween-20加5% w/v脱脂奶粉或BSA 10. 一抗的稀释：1X TBS,0.1% Tween-20 加 5% BSA ( 多抗) 或 5%脱脂奶粉( 单抗)。Note： 一般来说，BSA被推荐用于多克隆抗体

    查看更多相关实验 >
    图标技术资料

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    Thymosin beta 4 多克隆抗体 19850-1-AP
    ￥1350 - 3000