- ￥1350 - 3000
- Proteintech
- 19493-1-AP
- 2025年10月13日
- WB, IF/ICC, ELISA
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IF/ICC, ELISA
- 靶点：
VLDLR
- 抗体英文名：
VLDLR Polyclonal antibody
- 抗体名：
VLDLR Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | MCF-7 cells |
| Positive IF/ICC detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19493-1-AP targets VLDLR in WB, IF/ICC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, ELISA |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse, rat, chicken, zebrafish |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | very low density lipoprotein receptor |
| 别名 | VLDL-R, VLDL receptor, Very low-density lipoprotein receptor |
| 计算分子量 | 96 kDa |
| 观测分子量 | 96 kDa |
| GenBank蛋白编号 | NM_003383 |
| 基因名称 | VLDLR |
| Gene ID (NCBI) | 7436 |
| RRID | AB_10644342 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P98155 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
VLDLR binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. VLDLR binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (cytoplasmic domain of low-density lipoprotein receptor). For glycosylated, the MW of VLDLR migrates to ~160kd.
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文献和实验| Species | Application | Title |
|---|---|---|
| zebrafish | WB | Neuron Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.Authors - Hilliard Austin T AT |
| mouse | WB | Food Funct Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J miceAuthors - Rui Guo |
| rat | WB | Front Pharmacol Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats.Authors - Xue Wu |
| mouse | WB | PLoS One Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.Authors - Limin Liu |
| mouse | WB | Front Nutr Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcoholAuthors - Rui Guo |
| human | WB,IF | Front Oncol VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent functionAuthors - Mengying Yang
|
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