- ￥1350 - 3000
- Proteintech
- 16169-1-AP
- 2025年10月13日
- WB, IHC, IF/ICC, IF-P, ELISA
- Rabbit
- human, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
None
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IHC, IF/ICC, IF-P, ELISA
- 靶点：
SLC30A8/ZNT8-Specific
- 抗体英文名：
SLC30A8/ZNT8-Specific Polyclonal antibody
- 抗体名：
SLC30A8/ZNT8-Specific Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | mouse pancreas tissue |
| Positive IHC detected in | human pancreas tissue, human pancreas cancer tissue, human liver cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | human pancreas tissue |
| Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
16169-1-AP targets SLC30A8/ZNT8-Specific in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, IF-P, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat, yellow catfish |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | solute carrier family 30 (zinc transporter), member 8 |
| 别名 | SLC30A8, ZnT 8, Proton-coupled zinc antiporter SLC30A8, ZNT8, ZnT-8 |
| 计算分子量 | 41 kDa |
| 观测分子量 | 45-50 kDa |
| GenBank蛋白编号 | NM_173851 |
| 基因名称 | SLC30A8 |
| Gene ID (NCBI) | 169026 |
| RRID | AB_10733889 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8IWU4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SLC30A8 (also named as ZNT8) encods the secretory granule zinc transporter, permiting cellular efflux of zinc. SLC30A8 was recently defined as a autoantigen candidates of type 2 diabetes, although the molecular mechanism through which this phenotype is manifest is incompletely understood.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | WB | J Biol Chem Lipid-tuned Zinc Transport Activity of Human ZnT8 Correlates with Risk for Type-2 Diabetes.Authors - Chengfeng Merriman |
| rat | WB | J Biol Chem PMID: 28130446Authors - Qiong Huang |
| mouse | WB | J Biol Chem A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.Authors - Chengfeng Merriman |
J Biol Chem Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8.Authors - Chengfeng Merriman | ||
| human | WB | J Endocrinol Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine induced cell death.Authors - Maria Karsai |
| human | IHC | Sci Rep A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.Authors - Shogo Ohta |
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