- ￥1350 - 3000
- Proteintech
- 12259-1-AP
- 2025年10月13日
- WB, IHC, IF/ICC, ELISA
- Rabbit
- human, mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human SERPING1 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IHC, IF/ICC, ELISA
- 靶点：
SERPING1/C1 Inactivator
- 抗体英文名：
SERPING1/C1 Inactivator Polyclonal antibody
- 抗体名：
SERPING1/C1 Inactivator Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | human plasma, HeLa cells, human liver tissue, L02 cells, mouse liver tissue, HepG2 cells, human urine tissue |
| Positive IHC detected in | human tonsillitis tissue, human normal colon Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
12259-1-AP targets SERPING1/C1 Inactivator in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, IHC, IF/ICC, ELISA |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag2819 Product name: Recombinant human SERPING1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 151-500 aa of BC011171 Sequence: LKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFMLWDQQHKFPVFMGRVYDPRA |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| 别名 | Serpin G1, SERPING1, C1NH, C1-inhibiting factor, C1IN |
| 计算分子量 | 500 aa, 55 kDa |
| 观测分子量 | 100 kDa |
| GenBank蛋白编号 | BC011171 |
| 基因名称 | SERPING1 |
| Gene ID (NCBI) | 710 |
| RRID | AB_2285663 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P05155 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein. Of its 95-105 kDa apparent molecular mass, the protein moiety of 500 aa accounts for only 55 kDa. The native 105 kDa form of C1INH could be cleaved into 60-65 kDa fragments.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验| Species | Application | Title |
|---|---|---|
| mouse | WB | Glia Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits.Authors - Dorit Farfara |
| mouse | IF | J Neuroinflammation Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway.Authors - Yinquan Fang |
| human | WB | J Thromb Haemost The Alzheimer's disease peptide Aβ promotes thrombin generation through activation of coagulation factor XII.Authors - Daria Zamolodchikov |
| mouse | WB | J Thromb Haemost The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII: reply.Authors - D Zamolodchikov |
| Mouse | Nutrients New Mechanisms of Bromelain in Alleviating Non-Alcoholic Fatty Liver Disease-Induced Deregulation of Blood Coagulation.Authors - Po-An Hu | |
| human | IHC | J Alzheimers Dis A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome Technology.Authors - Koji Abe |
CUSABIO季度文献盘点：二季度新增600篇产品引用文献，总文献数量已达 31400篇！
(IgG) ELISA Kit; CSB-E11194mMouse anti-nuclear Antibody (IgG) ELISA Kit; CSB-E12912m 研究亮点 甲羟戊酸通路产物GGPP通过GGTase II催化RAB35香叶基香叶基化，促进CXCR5循环至细胞膜，维持T滤泡辅助细胞表面分子表达与分化。TCR信号经SREBP2、EGR1和E2F1增强该通路，在狼疮中异常活跃。他汀类药物抑制该通路，减轻自身免疫，提示代谢调控Tfh细胞的新机制。 05
：单克隆抗体设立相应亚型的对照，而多克隆抗体需要对应种属的 IgG 作为对照。用血球计数法或是其他方法对细胞计数。 1. 将 0.5-1 x 106 个细胞分到各检测管中（依照体积）。 2. 各管加入 2-3 ml 孵育缓冲液漂洗，离心回收细胞。重复一次。 3. 将每个管中的细胞重悬在 100 µl 孵育缓冲液中。 4. 室温，孵育缓冲液封闭 10 分钟。 5. 按合适的稀释比例在检测管中加入未标记，生物素标记或是荧光素标记的一抗。具体的用量参考抗体各自的说明书。
因此，综合来说，EarthOx的GST标签抗体 （货号#E022040）是一款同时具有高特异性、高灵敏度、多应用类型以及性价比的GST标签抗体。同时，我们也提供其他品牌的GST标签抗体，如Proteintech的GST多克隆抗体 ――GST PolyClonal Antibody（货号#10000-0-AP）以及Abcam、Santa等多种GST标签抗体产品。更多GST标签抗体以及其他如His、HA、Myc、GFP、Flag等其他标签抗体，请电话垂询。美国EarthOx品牌是一家提供高性价比免疫学和细胞
技术资料暂无技术资料 索取技术资料
