产品名称:重组人泛素结合酶E2-T(UBCE2T)
英文名称:Recombinant Human Ubiquitin-Conjugating Enzyme E2 T
产品货号:JN1966
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Val197在N端含有His标签。
UBCE2T质量控制:>95%(还原性SDS-PAGE)
UBCE2T制剂:液体
UBCE2T保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于UBCE2T:
Ubiquitin-Conjugating Enzyme E2 T (UBCE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBCE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBCE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues, but may prefer Lys-11-, Lys-27-, Lys-48- and Lys-63-linked polyubiquitination. UBCE2T is an important factor of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.