相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
- 保质期:
12 months from the shipping date of the product.
- 英文名:
Human Tau (K18) protein, mutant P301L (Pre-formed Fibrils)
- 库存:
Available
- 供应商:
GeneTex
- 规格:
200 μg/100 μg
| 规格: | 200 μg | 产品价格: | ¥9700.0 |
|---|---|---|---|
| 规格: | 100 μg | 产品价格: | ¥6200.0 |
Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau preformed fibrils (GTX17675-pro). Tau preformed fibrils (GTX17675-pro) seed the formation of new tau fibrils when combined with tau monomers (GTX17672-pro). Thioflavin T ex = 450 nm, em = 485 nm.
SDS-PAGE of ~15 kDa Human Tau (K18) protein, mutant P301L (preformed fibrils (PFFs)) (GTX17675-pro).
Lane 1: MW Ladder. Lane 2: Human Tau (K18) protein, mutant P301L (fibrils) (GTX17675-pro).
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
- 作者
- 内容
- 询问日期
文献和实验,共有 441 个氨基酸残基,其他亚型的结构及标记如下图。其中 K18 和 K19 是截短的 Tau 蛋白,仅含有微管结合重复区域。和 α- 突触核蛋白 PFFs(Pre-formed Fibrils) 相似的是,Tau PFFs 也被称为「种子」,有催化可溶性 Tau 蛋白聚集形成纤维缠结的作用。而与 α- 突触核蛋白 PFFs 不同的是,Tau PFFs 在正常神经细胞中的催化作用要慢得多,这是因为突变的 α- 突触核蛋白单体(A53T)在正常神经细胞中就存在,并且集中于神经突触前体末端,而突变
DamIP: Using Mutant DNA Adenine Methyltransferase to Study DNA‐Protein Interactions In Vivo
for studying DNA?protein interaction in vivo. A mutant form of DNA adenine methyltransferase (DamK9A) from E. coli is fused to the protein of interest and expressed. The fusion protein will bind to target binding sites and introduce N 6 ?adenine methylation
Interaction Trap/Two‐Hybrid System to Identify Loss‐of‐Interaction Mutant Proteins
., Chertkov, H., and Brent, R. 1993. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75:791‐803. Lin‐Goerke, J.L., Robbins, D.J., and Burczak, J.D
技术资料暂无技术资料 索取技术资料










