L-α-Aminoadipic acid,a gliotoxic analogue of glutamate,has been shown to competitively inhibit the transport protein of D-[3H]-aspartate.Experiments have reported that this compound also causes a reduction in ischemic glutamate release in murine hippocampal slices in vitro.Additional research suggests that L-α-Aminoadipic acid inhibits astrocyte culture Kynurenic acid synthesis which demonstrates the ability to modulate neuronal degeneration.L-α-Aminoadipic acid is a inhibitor of GluR and Gl Syn.