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- 钦诚生物
- 中国
- QC-3724R
- 2025年07月11日
- 兔
- 多物种
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
负20度
- 克隆性：
多克隆
- 适应物种：
多物种
- 保质期：
一年
- 库存：
大量
- 宿主：
兔
- 浓度：
1mg/ml
- 抗体英文名：
Phospho-mu Opioid Receptor (Ser375)
- 规格：
100ul
| 英文名称 | Phospho-mu Opioid Receptor (Ser375) |
| 中文名称 | 磷酸化µ-型受体抗体 |
| 别 名 | Mu Opioid Receptor (phospho S375); LMOR; MOR 1; mor; MOR1; Mu opiate receptor; mu type opioid receptor; Mu type opioid receptor MOR 1; muOR; Opioid receptor mu 1; Opioid receptor mu; OPRM; OPRM1; OPRM_RAT. |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | IHC-P=1:400-800 IHC-F=1:400-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from rat mu Opioid Receptor around the phosphorylation site of Ser375:HP(p-S)TA |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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文献和实验Mu-opioid receptor (MOR) belongs to a family of heptahelical G-protein-coupled receptors (GPCRs). Studies in humans and rodents demonstrated that the OPRM1 gene coding for MOR undergoes extensive alternative splicing afforded
resolution. Moreover, the downstream consequences following release and receptor binding are numerous and also difficult to measure with cellular resolution. Following repeated stressor exposure, dynorphin is released, binds to the kappa opioid receptor (KOR
In Vitro Opioid Receptor Assays
analgesics have been used for centuries, identification of opioid receptors and the ability of an opioid receptor antagonist to block natural pain processes prompted a search for endogenous opioid peptides. In vitro models were needed to characterize opioid
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