This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.
实验图
Immunohistochemistry of paraffin-embedded Cervical cancer(hu) using KDM1 at dilution of 1:100 (x100 lens,x200 lens).