Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.
Swiss Prot
Q9NWZ3
Gene ID
51135
亚细胞定位
Cytoplasm
宿主
Rabbit
克隆类型
Polyclonal Antibody
亚型
IgG
蛋白分子量
52kDa
稀释比例
WB 1:500-2000. IHC 1:25-100.
免疫原
A synthetic peptide of human IRAK4
Public Immunogen Range
A synthetic peptide of human IRAK4
纯化方法
Affinity purification
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存
Store at -20°C. Avoid freeze / thaw cycles.
性状
液体
交叉反应
Human
应用
WB IHC
规格
50ul 100ul
单位
支
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with IRAK4 antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using IRAK4 at dilution of 1:50 (x100 lens,x200 lens).