Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
实验图
Western blot analysis with SQSTM1 antibody at dilution at 1:1000
Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using SQSTM1 at dilution of 1:100 (x100 lens,x200 lens).
Immunohistochemistry of paraffin-embedded Breast cancer(hu) using SQSTM1 at dilution of 1:100 (x100 lens,x200 lens).
Immunohistochemistry of paraffin-embedded Cervical cancer(hu) using SQSTM1 at dilution of 1:100 (x100 lens,x200 lens).
Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using SQSTM1 at dilution of 1:100 (x100 lens,x200 lens).