Anti-MYC Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-MYC Polyclonal Antibody
别名	BHLHE39;c-Myc;MRTL;MYCC
中文名称	原致癌基因蛋白抗体
宿主	Rabbit
稀释比例	WB 1:2000-5000.IHC 1:50-200.
Gene ID	4609
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P01106
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
蛋白分子量	49kDa
亚细胞定位	Nucleus nucleolus nucleoplasm
免疫原	A synthetic peptide of human MYC
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Public Immunogen Range	A synthetic peptide of human MYC
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with MYC antibody at dilution at 1:1000

Immunohistochemistry of paraffin-embedded Colorectal cancer(hu) using MYC at dilution of 1:100 (x100 lens,x200 lens).

Immunohistochemistry of paraffin-embedded Pancreatic cancer(hu) using MYC at dilution of 1:100 (x100 lens,x200 lens).