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- 详细信息
- 技术资料
- 免疫原:
A synthetic peptide of human GCR
- 亚型:
IgG
- 形态:
液体
- 保存条件:
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 标记物:
详询
- 适应物种:
Human
- 保质期:
现询
- 抗原来源:
现询
- 目录编号:
K101529P
- 级别:
现询
- 库存:
99
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
现询
- 靶点:
GCR
- 抗体英文名:
Anti-NR3C1 Polyclonal Antibody
- 抗体名:
GCCR;GCR;GCRST;GR;GRL
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
产品简介
| 单位 | 支 |
| 英文名称 | Anti-NR3C1 Polyclonal Antibody |
| 别名 | GCCR;GCR;GCRST;GR;GRL;glucocorticoid receptor |
| 中文名称 | 核受体亚家族3,C组成员1抗体 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:3000. |
| Gene ID | 2908 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P04150 |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 蛋白分子量 | 52/76/61/65/82/86kDa |
| 亚细胞定位 | Cytoplasm Mitochondrion Nucleus Nucleus |
| 免疫原 | A synthetic peptide of human NR3C1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. |
| Public Immunogen Range | 30-80/777aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul 100ul |
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with GCR antibody at dilution at 1:1000
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Anti-GCR Polyclonal Antibody
¥960 - 1600











