Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Cytoplasm
免疫原
Recombinant protein of human DOK4
亚型
IgG
性状
液体
纯化方法
Affinity purification
背景资料
Docking protein 4?is a?protein?that in humans is encoded by the?DOK4?gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Public Immunogen Range
Recombinant protein of human DOK4
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
WB IHC
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with DOK4 antibody diluted at 1:1000;Lane: MCF7,MDA-MB-231
Immunohistochemistry of paraffin-embedded Rat brain with DOK4 antibody diluted at 1:30