- ￥960
- Solarbio
- K112436P-50ul
- 北京
- 2026年01月14日
- WB
- Rabbit
- Human;Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
RAD17
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Human;Mouse
- 保质期：
一年
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 亚型：
IgG
- 免疫原：
Recombinant protein of human RAD17
- 规格：
50ul
产品简介
| 中文名称 | 细胞周期检查点蛋白RAD17抗体 |
| 靶标 | RAD17 |
| 别名 | CCYC; Cell cycle checkpoint protein; Cell cycle checkpoint protein RAD17; FLJ41520; HRAD 17; hRad17; R24L; Rad 17; Rad 24; RAD1 (S. pombe) homolog; RAD1 homolog; RAD17; RAD17 homolog (S. pombe); RAD17 homolog; Rad17 like protein; RAD17, S. pombe, homolog of; RAD17_HUMAN; RAD17Sp; Rad24; Rad24, mouse, homolog of; Rad24, S. cerevisiae, homolog of; RF C activator 1 homolog; RF C/activator 1 homolog; RF-C/activator 1 homolog |
| 背景资料 | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. |
| Swiss Prot | O75943 |
| Gene ID | 5884 |
| 亚细胞定位 | Nucleus |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 预测交叉反应 | Monkey;Orangutan |
| 蛋白分子量 | 57/66/76/77kDa |
| 实际分子量 | 72kDa |
| 稀释比例 | WB 1:1000-3000. |
| 免疫原 | Recombinant protein of human RAD17 |
| Public Immunogen Range | 1-350aa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| 交叉反应 | Human;Mouse |
| 应用 | WB |
| 规格 | 50ul 100ul |
| 单位 | 支 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
"Western blot analysis with RAD17 antibody diluted at 1:2000;Lane: U937
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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