Anti-CALM2 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-CALM2 Polyclonal Antibody
别名	CAMII;LQT15;PHKD;PHKD2;caM
宿主	Rabbit
稀释比例	WB 1:500-2000.
Gene ID	805
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P62158
蛋白分子量	17kDa
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm cytoskeleton spindle spindle pole
免疫原	Recombinant protein of human CALM2
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Public Immunogen Range	Recombinant protein of human CALM2
克隆类型	Polyclonal Antibody
交叉反应	Human Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with CALM2 antibody diluted at 1:1000