Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位
Endoplasmic reticulum
免疫原
Recombinant protein of human DPM1
亚型
IgG
性状
液体
纯化方法
Affinity purification
背景资料
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
Public Immunogen Range
Recombinant protein of human DPM1
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
WB IF
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with DPM1 antibody diluted at 1:1000