This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Public Immunogen Range
Recombinant protein of human DNAJA3
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
WB
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with DNAJA3 antibody diluted at 1:1000;Lane:BT-474,Jurkat,293T,HepG2,Mouse liver,Mouse kidney,Mouse heart,Rat liver
Immunohistochemistry of paraffin-embedded Rat brain with DNAJA3 antibody diluted at 1:100