Appetite regulating hormone;Ghrelin Obestatin;GHRL;Growth hormone secretagogue;Motilin related peptide;MTLRP;obestatin;Protein M46
规格:
50ul/100ul
规格:
50ul
产品价格:
¥960.0
规格:
100ul
产品价格:
¥1600.0
产品简介
英文名称
Anti-GHRL Polyclonal Antibody
宿主
Rabbit
别名
Appetite regulating hormone;Ghrelin Obestatin;GHRL;Growth hormone secretagogue;Motilin related peptide;MTLRP;obestatin;Protein M46
稀释比例
WB 1:1000-3000. IHC 1:50-200.
蛋白分子量
7/9/11/13kDa
Gene ID
51738
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG
免疫原
Recombinant protein of human GHRL
亚细胞定位
Cytoplasm
Swiss Prot
Q9UBU3
背景资料
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
Public Immunogen Range
1-117aa
克隆类型
Polyclonal Antibody
交叉反应
Human
应用
WB IHC
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Western blot analysis with GHRL antibody diluted at 1:2000;Lane: HL-60
Immunohistochemistry of paraffin-embedded Human colorectal cancer with GHRL antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded Human renal cancer with GHRL antibody diluted at 1:100