Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位
Lysosome
免疫原
Recombinant protein of human HEXA
亚型
IgG
性状
液体
纯化方法
Affinity purification
背景资料
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Public Immunogen Range
Recombinant protein of human HEXA
克隆类型
Polyclonal Antibody
交叉反应
Human Rat Mouse
应用
WB IHC
规格
50ul 100ul
备注: 以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。 These protocols are for reference only. Solarbio does not independently validate these methods. 温馨提示: 使用前请离心。如有问题请及时联系我们。 Quick spin before use. If you have any questions, please contact us. 实验图 Immunohistochemistry of paraffin-embedded rat testis tissue using HEXA antibody at dilution of 1:100 (x40 lens).