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Anti-CBL Polyclonal Antibody

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  • ¥960 - 1600
  • Solarbio已认证
  • 北京
  • 2025年10月01日
  • Rabbit
  • Human Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant protein of human CBL

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at -20°C. Avoid freeze / thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human Mouse

    • 目录编号

      K001741P

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 靶点

      CBL

    • 抗体英文名

      Anti-CBL Polyclonal Antibody

    • 抗体名

      C-CBL;CBL2;FRA11B;NSLL;RNF55

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    产品简介
    单位
    英文名称 Anti-CBL Polyclonal Antibody
    别名 C-CBL;CBL2;FRA11B;NSLL;RNF55
    宿主 Rabbit
    稀释比例 WB 1:500-2000.IHC 1:50-100
    Gene ID 867
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    Swiss Prot P22681
    蛋白分子量 100kDa
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    亚细胞定位 Cell membrane Cytoplasm
    免疫原 Recombinant protein of human CBL
    亚型 IgG
    性状 液体
    纯化方法 Affinity purification
    背景资料 This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder.
    Public Immunogen Range Recombinant protein of human CBL
    克隆类型 Polyclonal Antibody
    交叉反应 Human Rat Mouse
    应用 WB IHC
    规格 50ul 100ul

    备注:
    以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
    These protocols are for reference only. Solarbio does not independently validate these methods.
    温馨提示:
    使用前请离心。如有问题请及时联系我们。
    Quick spin before use. If you have any questions, please contact us.
    实验图
    产品细节图片1
    Western blot analysis with CBL antibody diluted at 1:1000
    产品细节图片2
    Immunohistochemistry of paraffin-embedded human prostate using CBL antibody at dilution of 1:200 (x40 lens).
    Anti-CBL Polyclonal Antibody
    宿主 Rabbit
    别名 C-CBL;CBL2;FRA11B;NSLL;RNF55
    稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-200.
    蛋白分子量 100kDa
    Gene ID 867
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human CBL
    性状 液体
    Public Immunogen Range Recombinant protein of human CBL
    亚细胞定位 Cell membrane Cytoplasm
    Swiss Prot P22681
    克隆类型 Polyclonal Antibody
    背景资料 This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder.
    应用    WB IHC IF
    交叉反应    Human Mouse
    规格    50ul    100ul

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

    暂无技术资料 索取技术资料

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