Anti-YBX1 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-YBX1 Polyclonal Antibody
别名	BP-8;CBF-A;CSDA2;CSDB;DBPB;EFI-A;MDR-NF1;NSEP-1;NSEP1;YB-1;YB1
宿主	Rabbit
稀释比例	WB 1:500-2000. IHC 1:100-200. IF 1:50-200.
Gene ID	4904
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P67809
蛋白分子量	36kDa
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位	Nucleus Cytoplasm Secreted
免疫原	A synthetic peptide of human YBX1
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.
Public Immunogen Range	A synthetic peptide of human YBX1
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IF IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with YBX1 antibody diluted at 1:1000

Immunohistochemistry of paraffin-embedded human lung cancer using YBX1 antibody at dilution of 1:100 (x40 lens).

Immunofluorescence analysis of HeLa cells using YBX1 antibody (A7704) at dilution of 1:100. Blue: DAPI for nuclear staining.