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Anti-FAS Polyclonal Antibody

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  • ¥960 - 1600
  • Solarbio已认证
  • 北京
  • 2025年07月15日
  • Rabbit
  • Human Mouse Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      A synthetic peptide of human FAS

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at -20°C. Avoid freeze / thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human Mouse Rat

    • 目录编号

      K000322P

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 靶点

      FAS

    • 抗体英文名

      Anti-FAS Polyclonal Antibody

    • 抗体名

      ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Anti-FAS Polyclonal Antibody
    宿主 Rabbit
    别名 ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6
    稀释比例 WB 1:500-2000. IHC 1:50-100.
    蛋白分子量 38kDa
    Gene ID 355
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 A synthetic peptide of human FAS
    性状 液体
    Public Immunogen Range A synthetic peptide of human FAS
    亚细胞定位 Cell membrane Secreted Single-pass type I membrane protein
    Swiss Prot P25445
    克隆类型 Polyclonal Antibody
    背景资料 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
    应用    WB IHC
    规格    50ul    100ul

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

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