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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic Peptide
- 亚型:
IgG1
- 形态:
液体
- 保存条件:
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 适应物种:
Human
- 目录编号:
K000212M
- 库存:
999
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Mouse
- 靶点:
PARP
- 抗体英文名:
Anti-PARP Monoclonal Antibody
- 抗体名:
ADPRT;ADPRT1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥960.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 英文名称 | Anti-PARP Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 别名 | ADPRT;ADPRT1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL |
| 稀释比例 | WB 1:1000-3000. IHC 1:200-500. |
| 蛋白分子量 | 116/89kDa |
| Gene ID | 142 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Saturated ammonium sulfate precipitation |
| 亚型 | IgG1 |
| 免疫原 | Synthetic Peptide |
| 性状 | 液体 |
| Public Immunogen Range | Synthetic Peptide |
| 亚细胞定位 | Nucleus nucleolus |
| Swiss Prot | P09874 |
| 克隆号 | M3 |
| 克隆类型 | Monoclonal Antibody |
| 背景资料 | Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate. |
| 应用 | WB IHC |
| 交叉反应 | Human |
| 规格 | 50ul 100ul |
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文献和实验PARP1 Genomics: Chromatin Immunoprecipitation Approach Using Anti-PARP1 Antibody (ChIP and ChIP-seq)
Poly(ADP-ribose) polymerase1 (PARP1) is a global regulator of different cellular mechanisms, ranging from DNA damage repair to control of gene expression. Since PARP1 protein and pADPr have been shown to persist in chromatin through cell
指仅对一种抗原决定基的纯粹的抗体。这类抗体不可能通过将抗原 胞的 Hybridoma,在试管内制成了纯粹的单克隆抗体。用某种抗原使动物产生免疫感应,对应于抗原之不同部分可制成各种不同的抗体复合体。然而,因为一个产生抗体的细胞,只能产生一种抗体,所以骨髓肿瘤细胞与产生抗体细胞间的细胞杂种,可形成边产生抗体边增殖的 hybridoma,将每个杂种细胞进行克隆(无性繁殖系)培养,则一个克隆的细胞群只由单种类产生同一抗体的细胞所组成,这样得到的就是单克隆抗体。此抗体在测定
Monoclonal Antibody Production
Order 6 six week old Balb/C mice and let the ARC know they are coming.Have your antigen ready for when they arrive.Once they get there earmark the mice and perform a pre-bleed on them to be used as an ELISA control for monitoring the titer
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